RPHR -- Wise et al. 57 (1): 235 Figure 1

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FIG. 1. The luteinizing hormone (LH) surge is blunted and delayed in middle-aged, compared to young, rats. Young and middle-aged regularly cycling rats were sequentially bled from right atrial cannulae during the day of proestrus. Plasma was radioimmunoassayed for LH. The first significant increase in LH was delayed by 1 hour and attenuated significantly in middle-aged rats.