Drug Dose Mean percentage inhibition Reference Aminoglutethimide (+ hydrocortisone) 1000 mg (+ 40 mg)/d 90.6 MacNeill et al., 1992 Formestane 250 mg/2 w (im) 84.8 Jones et al., 1992 Fadrozole 2 mg/d 82.4 Lonning et al., 1991 Vorozole 1 mg/d 93.0 Van der Wall et al., 1993 Letrozole 2.5 mg/d > 99.1 Geisler et al., 2001 Anastrozole 1 mg/d 97.3 Geisler et al., 2001 Exemestane 25 mg/d 97.9 Geisler et al., 1998

[All analyses, other than Van der Wall et al. (1993) were conducted in the Dowsett laboratory.]

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