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TABLE III Genes Specifically Affected by IGF-1 in Breast Epithelial Cells

B-cell lymphoma-2 interacting killer
c-fos
Cytochrome P450 1A1 and 1B1
Ferrodoxine reductase
GADD45 (growth arrest and DNA damage)
Interleukin 1 beta
Jun B
Low-density lipoprotein-related protein
Plasminogen activator inhibitor-1
Transferrin
Vascular endothelial growth factor

[Adapted from Oh JS, Kucab JE, Bushel PR, Martin K, Bennett L, Collins J, DiAugustine RP, Barrett JC, Afshari CA, Dunn SE 2002 Insulin-like growth factor-1 inscribes a gene expression profile for angiogenic factors and cancer progression in breast epithelial cells. Neoplasia 4:204–217.]





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