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FIG. 1. A diagram representing stimulation of the arcuate nucleus of the hypothalamus (ARC) by leptin and insulin. A neuroanatomical schematic of the hypothalamic melanocortin system control of food intake. Abbreviations: PVN, paraventricular nucleus; LHA, lateral hypothalamic area; NPY, neuropeptide Y; AgRP, agouti-related protein; MSH, melanocyte-stimulating hormone; CART, cocaine- and amphetamine-regulated transcript.
