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TABLE IV Four Polymorphisms of the GR Gene, Studied in the Same Population in Relation to Glucocorticoid Sensitivity

Polymorphism BclI N363S ER22/23EK TthIIII
N 191 216 202 205
Fasting cortisol ND ND ND ND
Sensitivity to 1-mg DEX Increased ND Decreased ND
Sensitivity to 0.25-mg DEX Increased Increased ND ND

[Abbreviations: N, number; DEX, dexamethasone; ND, no differences between genotype groups of the above-mentioned polymorphism.]





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